Methylation and its Importance to Health
Event on 2016-01-21 13:30:00
Methylation and its Importance to Health 'Methylation and its Importance to Health' has been approved by the Federation of the Royal Colleges of Physicians of the United Kingdom for 3 category 1 (external) CPD credit(s). Also approved for 2 1/2 hours CPD by BANT (British Association for Applied Nutrition & Nutritional Therapy). Two top speakers with a fascinating insight into the following topics: 1. The development of the brain and the peripheral neuroimmune system – Dr Jaleel Miyan A new perspective on the prevention and treatment of a variety of medical and neurological conditions. Neurodevelopmental deficiencies and disorders affect perhaps as many as 10% of live human births and have had a lot of research attention with not much impact so far, most particularly for autism, which is increasing at an alarming rate. Scans of student populations in the USA demonstrate that 10% of these individuals also have reduced cerebral cortex thickness, indicating a hiccup in the developmental process with little, if any, impact on their abilities and achievements in higher education. So what is the difference between developmental events that lead to neurological conditions such as autism, schizophrenia, bipolar, epilepsy and other abnormalities, and those developmental events that have no apparent impact on brain function and life achievements? As well as factors interfering in brain development, another important aspect may be that researchers have focused on the brain alone rather than on the integrated whole nervous system and its associations with peripheral body organs, systems and functions. Dr Jaleel Miyan BSc, PhD, FHEA Dr Jaleel Miyan is a Senior Lecturer in Neuroscience at the University of Manchester. His main research interests are in the role of cerebrospinal fluid in cerebral cortex development and in conditions where this goes wrong including hydrocephalus and autism. In recent years his group have identified a unique cerebral folate handling system that also provides a route to treat and prevent poor cortical development. His other main research areas are in neuroimmunology and specifically in the hard-wired neural control system underlying host defence and immunity. Recently these two research areas have come together in a novel hypothesis to explain autism as a condition based in neuroimmune malfunctions that precipitate central neural changes underlying the behavioural abnormalities seen in these conditions. Jaleel received his Bachelor's degree from the University of Sussex, his PhD from Glasgow University and held a Royal Society Research Fellowship for 10 years before taking up his post at Manchester. He has published more than 90 papers and is a Fellow of the Royal Microscopical Society and a Fellow of the Higher Education Academy. 2. Management of patients with MTHFR mutation – Dr Tapan Audhya Polymorphism in gene encoding one of the folate metabolizing enzymes MTHFR (C 677T and A 1298C) has been linked to multiple pathophysiological consequences. This anomaly is either inherited or due to exogenous toxic agents or to endogenous processes. This enzyme is responsible for the process of methylation in every cell of our body. Genetic variant of this enzyme causes it to function at a much lower than normal rate. The MTHFR anomaly could be either homozygous or heterozygous. In this presentation we will share some of our findings on the management of these patients using prescription medicines (Deplin, Metanx, Cerefolin-NAC, etc.), supplements of known structure and functions, and various minerals. These modulate the activity of the defective enzyme produced by polymorphic genes. The clinical outcome of this project will be discussed in detail. Dr Tapan Audhya PhD Dr Tapan Audhya PhD completed his undergraduate degree in Biochemistry in England and received his doctorate degree in Biochemistry and Chemistry of Natural Products from Dalhousie University, Canada. At present he is a Professor of Biochemistry and Endocrinology in New York University Medical School and also Director of R & D in the Health Diagnostics Research Institute, NJ. Prior to his recent responsibilities, he spent over fifteen years in basic research in the pharmaceutical industry in the USA. With over 200 published articles in refereed journals and books, Dr Audhya is recognized as an expert in the fields of Endocrinology, Metabolism and Nutritional Biochemistry. For the last ten years he has been involved in the aetiology of, and nutritional treatment for, autism, CSF and depression and presented many of his findings in national and international conferences. PARKING The Marlowes Shopping Centre, Wolsey Rd, Hemel Hempstead, Hertfordshire HP1 1DX The Marlowes Shopping Centre multi-storey car park is a few minutes' walk form Maple House and has over 1,200 parking spaces, including disabled and parent and child spaces. Disabled car parking spaces are available: in the Shopmobility area, accessible from the first entrance only on level C in the centre of the car park, accessible from both entrances on level D Red, accessible from both entrances Parent and child spaces are available: on level B Red, accessible from the second entrance only on level D Red, accessible from both entrances Opening hours: Monday: 8:00am – 6.30pm; Tuesday: 8:00am – 6.30pm; Wednesday: 8:00am – 6.30pm; Thursday: 8:00am – 8:00pm; Friday: 8:00am – 6.30pm; Saturday: 8.00am – 6.30pm; Sunday: 10.00am – 6.00pm Parking Rates: Up to 2 hours: £1.50; Up to 3 hours: £1.80; Up to 4 hours: £2.20; Up to 5 hours: £3.00; Up to 6 hours: £5.00; Over 6 hours: £15.00 Free parking after 5:00 pm on Thursdays. Half-price parking is available to disabled shoppers Monday to Saturday, by showing their blue/orange badge or Shopmobility card at the Customer Service Desk. On Sunday, parking is £1.00 all day for all customers. Tickets must be validated at one of the car park pay machines within the Centre prior to returning to the car park. Debit/Credit card payment is now accepted at all machines.
at Maple House, Breakspear Medical
Hertfordshire House , Wood Lane
Hemel Hempstead, United Kingdom
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